306 Xinsha Road, Shajing Street, Bao'an District,Shenzhen, Guangdong, China
বাড়ি পণ্যCancer Treatment Steroids

Shenzhen Sendi Biotechnology Co.Ltd.

Imatinib Mesylate Cancer Treatment Steroids / Pharmaceutical Raw Materials for Antitumor , 220127-57-1

    • Imatinib Mesylate Cancer Treatment Steroids / Pharmaceutical Raw Materials for Antitumor , 220127-57-1
    • Imatinib Mesylate Cancer Treatment Steroids / Pharmaceutical Raw Materials for Antitumor , 220127-57-1
  • Imatinib Mesylate Cancer Treatment Steroids / Pharmaceutical Raw Materials for Antitumor , 220127-57-1

    পণ্যের বিবরণ:

    Place of Origin: China
    পরিচিতিমুলক নাম: Sendi
    সাক্ষ্যদান: SGS,ISO9001
    Model Number: 220127-57-1

    প্রদান:

    Minimum Order Quantity: 10 Grams
    মূল্য: 1.5 usd dollars per gram
    Packaging Details: Discreet and safe foil bag
    Delivery Time: Within 12hours after payment
    Payment Terms: West Union, T/T, Money Gram.,Bitcorn and bank transfer, D/P
    Supply Ability: 10000 Kg
    এখন যোগাযোগ
    বিস্তারিত পণ্যের বর্ণনা
    Name: Imatinib Mesylate CAS: 220127-57-1
    Molecular Formula: C30H35N7O4S Description: White or off-white crystal powder
    MW: 589.71 Assay: 99%
    Category: Cancer Treatment Steroids Other name: IMATINIB BASE

    Imatinib Mesylate Cancer Treatment Steroids / Pharmaceutical Raw Materials for Antitumor , 220127-57-1

    Name

    Imatinib mesylate

     

    Other Name

    IMATINIB BASE

     

    CAS No.

    220127-57-1

     

    EINECS

    N/A

     

    MF

    C30H35N7O4S

     

    MW

    589.71

     

    MP

    214-224°C

     

    Storage temp.

    -20°C Freezer

     

    Purity

    99% min

     

    Usage

    echinocandin antifungal, active against infections with Aspergillus and Candida, inhibits cell wall synthesis

     

    Appearance

    Off-White Solid

     

     

    Product Description

    Imatinib mesylate is a tyrosine kinase inhibitor IC50 value of 100 nM, 100 nM, 600 nM for v-Abl, c-kit, PDGFR, respectively.

    Imatinib Mesylate is a specific tyrosine kinase (abl, c-kit, and PDGFR) inhibitor and is reported to sensitize cells to radio- or chemo-therapy. When tested with Y-79 and WERI-RB-1 Rb cell lines, imatinib mesylate treatment decreased the cell proliferation and invasion with the concentration of 10 μM .

     

    In osteoblast cells, administration of imatinib mesylate decreased osteoclast development via stimulating differentiation, inhibiting proliferation and survival 


    In dog model with mast cell tumor, administration of imatinib mesylate at a dose of 10 mg/kg daily for 1-9 weeks reduced tumor growth via inhibiting tyrosine kinase.


    Dosage
    ​​​​​​​
    Starting dose: in patients with chronic myelogenous leukemia radically increasing stage and accelerating stage, imatinib mesylate in the recommended dose of 600 mg/day; Chronic-phase of interferon treatment failure, and cannot be removed surgically or metastatic malignant gastrointestinal stromal tumors (GIST) patients, and the recommended dose of 400 mg/day, both for once-daily oral, appropriate medication when eating, and drinking a glass of water, as long as effective, should be continued.

    Applications

    Cells were stimulated with allogeneic mature DCs or PHA in the presence of imatinib mesylate. The drug inhibited T-cell proliferation as a function of concentration. The effects were significant at 0.5 μM imatinib mesylate for the cells stimulated by DCs and at 1.0 μM imatinib mesylate for the cells stimulated with PHA.

     

    The IC50 values for imatinib mesylate-inhibited T-cell proliferation stimulated by DCs and PHA were 3.9 μM and 2.9 μM, respectively..A tyrosine kinase inhibitor. Highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL)

    Imatinib Mesylate is orally bioavailability mesylate salt of Imatinib, which is a multi-target inhibitor of v-Abl, c-Kit and PDGFR with IC50 of 0.6 μM, 0.1 μM and 0.1 μM, respectively. Imatinib also known as Gleevec, Glivec, CGP-57148B, STI-571 & Imatinib

    Imatinib Mesylate (STI571) is an orally bioavailability mesylate salt of Imatinib, which is a multi-target inhibitor of v-Abl, c-Kit and PDGFR with IC50 of 0.6 μM, 0.1 μM and 0.1 μM, respectively.echinocandin antifungal, active against infections with Aspergillus and Candida, inhibits cell wall synthesis

    *************************************************************************************************************************************
    Package details:
    1kg/Aluminum foil bag
    1kg/ Aluminium Tin
    25kg/Drum
    25kg/ Aluminum Drum
    *************************************************************************************************************************************
    Delivery Time:
    Usually within 2 working days after confirming the payment.
    *************************************************************************************************************************************
    Shipping details:
    DHL; TNT; UPS or EMS

    *************************************************************************************************************************************
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    Imatinib Mesylate Cancer Treatment Steroids / Pharmaceutical Raw Materials for Antitumor , 220127-57-1

     

    Our commitment:

    1. Any inquiries will be replied within 12 hours.
    2. Dedication to quality, supply & service.
    3. Strictly on selecting raw materials.
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    5. Reasonable & competitive price, fast lead time.
    6. Sample is available for your evaluation & Formulation development.
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    (1) International Authorized Third-Party Test For The Products You Demand.
    (2) 60 Days Warranty of quality of goods.

     

     

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    Imatinib Mesylate Cancer Treatment Steroids / Pharmaceutical Raw Materials for Antitumor , 220127-57-1

    যোগাযোগের ঠিকানা
    Shenzhen Sendi Biotechnology Co.Ltd.

    ব্যক্তি যোগাযোগ: Demi

    টেল: +8618123940985

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